ATG13鼠单克隆抗体

品牌 商品编码 商品名称 规格 单位 单价
HAOKEBIO HK510012M ATG13鼠单克隆抗体 100ul 1960

Applications

Tested Applications:
IF, IHC, WB,ELISA

Species Specificity:
Human, Mouse, Rat, Pig

Positive WB detected in:
mouse brain tissue, BGC-823 cells, NIH/3T3 cells, pig brain tissue, rat brain tissue

Positive IHC detected in:

mouse testis tissue, mouse brain tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Positive IF detected in:
HEK-293 cells

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
KIAA0652

Calculated molecular weight:
57 kDa

Observed molecular weight:
57 kDa

Gene symbol
KIAA0652

Synonyms
ATG13, Autophagy related protein 13, FLJ20698, KIAA0652

Background

ATG13 is one component protein of the ULK1 complex which is required for autophagosome formation and mitophagy. ATG13 has two nutrient regulatory phosphorylation sites and the phosphorylation status of ATG13 affect regulation of autophagy by modulating enzyme activity and cellular localization of ULK1. Besides, it has been reported the nonautophagic function of ATG13 on cardiac development for ATG13-deficient embryos show myocardial growth defects.(PMID:27387056, 26801615, 26644405)

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