ARL13B鼠单克隆抗体

品牌 商品编码 商品名称 规格 单位 单价
HAOKEBIO HK510008L ARL13B鼠单克隆抗体 200ul 2800

Applications

Tested Applications:
IF, WB,ELISA

Cited Applications:
IF

Species Specificity:
Canine, Human, mouse, pig

Cited Species:
human, mouse, rat

Positive WB detected in:
HepG2 cells, HEK-293 cells, NCCIT cell

Positive IF detected in:
MDCK cells

Recommended dilution:
WB : 1:1000-1:6000
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ADP-ribosylation factor-like 13B

Calculated molecular weight:
48 kDa

Observed molecular weight:
60 kDa

Gene symbol
ARL13B

Synonyms
ARL13B, ARL2 like protein 1, ARL2L1, DKFZp686E2075, DKFZp686L2472, DKFZp686M2074, DKFZp761H079, JBTS8

Background

ARL13B, also named as ARL2L1, is a small ciliary G protein of the Ras superfamily. Localized in the cilia, it is required for cilium biogenesis and sonic hedgehog signaling. Defects in ARL13B are the cause of Joubert syndrome (JS) which is an autosomal recessive disorder characterized by a distinctive cerebellar malformation (PMID: 19906870). Arl13b is predicted to be a 48 kDa protein, and the 60 kDa band is likely to represent a modified form of Arl13b. ARL13B can be used to mark the cilia (PMID:22072986).

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