XBP1兔多克隆抗体

品牌 商品编码 商品名称 规格 单位 单价
HAOKEBIO HK210358L XBP1兔多克隆抗体 200ul 2800

Applications

Tested Applications:
IHC, WB, ELISA

Cited Applications:
IHC, WB

Species Specificity:
human, mouse

Cited Species:
human, mouse, rat

Positive WB detected in:
MDA-MB-453s cells

Positive IHC detected in:

human breast cancer tissue, human colon cancer tissue, human liver cancer tissue, mouse liver tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Recommended dilution:
WB : 1:200-1:1000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
X-box binding protein 1

Calculated molecular weight:
261 aa, 29 kDa

Observed molecular weight:
55 kDa, 30 kDa

Gene symbol
XBP1

Synonyms
TREB5, X box binding protein 1, XBP 1, XBP1, XBP1S, XBP1S-specific, XBP2

Background

X-box-binding protein 1 (XBP1), also named as TREB5, is a 261 amino acid protein, which contains one bZIP domain and belongs to the bZIP family. XBP1 localizes in the nucleus and as a transcription factor is essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response. XBP1 has an association with major affective disorder. The molecular weight of protein generated from the spliced XBP1 mRNA is 54 kDa and protein generated from unspliced Xbp1 mRNA is 33 kDa. This antibody 24868-1-AP specially recognizes isoform XBP-1S.

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