杭州浩克生物
CD19兔多克隆抗体
167Applications Product Information Immunogen Informatio Background
查看全文TLR4兔多克隆抗体
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| HAOKEBIO | HK210332M | TLR4兔多克隆抗体 | 100ul | 支 | 1960 |
Applications
Tested Applications:
IHC, WB,ELISA
Cited Applications:
CoIP, ELISA, IF, IHC, IP, Microtiter plate binding assay, WB
Species Specificity:
human, mouse, rat
Cited Species:
bovine, hamster, human, mouse, pig, rat
Positive WB detected in:
mouse liver tissue, Daudi cells, rat liver tissue
Positive IHC detected in:
human placenta tissue, human liver cancer tissue, mouse brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Recommended dilution:
WB : 1:500-1:1000
IHC : 1:100-1:400
Product Information
Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information
Full name:
toll-like receptor 4
Calculated molecular weight:
839 aa, 96 kDa
Observed molecular weight:
90-100 kDa
Gene symbol
TLR4
Synonyms
ARMD10, CD284, hToll, TLR4, TOLL, toll like receptor 4
Background
TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 interacts with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kB activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described. The calculated molecular weights of the three TLR4 isoforms are 96, 91, and 73 kDa.
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