杭州浩克生物
GORASP2兔多克隆抗体
119Applications Product Information Immunogen Information Background
查看全文PAX6兔多克隆抗体
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| HAOKEBIO | HK210271L | PAX6兔多克隆抗体 | 200ul | 支 | 2800 |
Applications
Tested Applications:
FC, IF, IHC, WB,ELISA
Cited Applications:
IF, IHC, WB
Species Specificity:
human, mouse, rat
Cited Species:
human, mouse, rat
Positive WB detected in:
Y79 cells, human stomach tissue, mouse embryo tissue, rat brain tissue
Positive IHC detected in:
mouse brain tissue, mouse embryo tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected in:
mouse brain tissue, iPS cells, Neuro-2a cells
Positive FC detected in:
SH-SY5Y cells
Recommended dilution:
WB : 1:500-1:3000
IHC : 1:500-1:2000
IF : 1:50-1:500
Product Information
Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information
Full name:
paired box 6
Calculated molecular weight:
47 kDa
Observed molecular weight:
47 kDa
Gene symbol
PAX6
Synonyms
AN, AN2, Aniridia type II protein, D11S812E, MGDA, Oculorhombin, paired box 6, Paired box protein Pax 6, PAX6, WAGR
Background
PAX6, a paired domain and homeodomain-containing transcription factor. Interaction with TRIM11 leads to ubiquitination of PAX6 and its proteasomal degradation. PAX6 is one of the earliest genes expressed in the eye field and considered a master control gene for retinal and eye development. PAX6 also regulates the development of the olfactory, central nervous systems, pituitary, and pancreas. PAX6 mutations can cause complex ocular disorders such as aniridia and Peter’s anomaly.
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