PAX6兔多克隆抗体

品牌 商品编码 商品名称 规格 单位 单价
HAOKEBIO HK210271L PAX6兔多克隆抗体 200ul 2800

Applications

Tested Applications:
FC, IF, IHC, WB,ELISA

Cited Applications:
IF, IHC, WB
Species Specificity:
human, mouse, rat

Cited Species:
human, mouse, rat

Positive WB detected in:
Y79 cells, human stomach tissue, mouse embryo tissue, rat brain tissue

Positive IHC detected in:

mouse brain tissue, mouse embryo tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Positive IF detected in:
mouse brain tissue, iPS cells, Neuro-2a cells

Positive FC detected in:
SH-SY5Y cells

Recommended dilution:
WB : 1:500-1:3000
IHC : 1:500-1:2000
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

 

Full name:
paired box 6

Calculated molecular weight:
47 kDa

Observed molecular weight:
47 kDa

Gene symbol
PAX6

Synonyms
AN, AN2, Aniridia type II protein, D11S812E, MGDA, Oculorhombin, paired box 6, Paired box protein Pax 6, PAX6, WAGR

Background

PAX6, a paired domain and homeodomain-containing transcription factor. Interaction with TRIM11 leads to ubiquitination of PAX6 and its proteasomal degradation. PAX6 is one of the earliest genes expressed in the eye field and considered a master control gene for retinal and eye development. PAX6 also regulates the development of the olfactory, central nervous systems, pituitary, and pancreas. PAX6 mutations can cause complex ocular disorders such as aniridia and Peter's anomaly.

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