杭州浩克生物
Caspase 6兔多克隆抗体
127Applications Product Information Immunogen Information Background
查看全文p63兔多克隆抗体
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| HAOKEBIO | HK210266S | p63兔多克隆抗体 | 50ul | 支 | 1200 |
Applications
Tested Applications:
IF, IP, WB,ELISA
Cited Applications:
ChIP, IF, IP, WB
Species Specificity:
human, mouse, rat
Cited Species:
human, mouse, rat
Positive WB detected in:
A431 cells, Apoptosised HeLa cells, human heart tissue, mouse heart tissue, U-937 cells
Positive IP detected in:
A431 cells
Positive IF detected in:
A431 cells
Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IF : 1:50-1:500
Product Information
Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information
Full name:
tumor protein p63
Calculated molecular weight:
680 aa, 77 kDa
Observed molecular weight:
63-68 kDa
Gene symbol
TP63
Synonyms
AIS, B(p51A), B(p51B), CUSP, EEC3, KET, LMS, NBP, OFC8, p40, p51, p53CP, p63, p73H, p73L, RHS, SHFM4, TP53CP, TP53L, TP63, TP73L, Tumor protein 63, tumor protein p63, Tumor protein p73 like
Background
TP63, also named KET, P63, P73H, P73L and TP73L, belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd(P40), 50kd(P60),63kd(P63) and 73kd(P73L). It is Nuclear stain.
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