抗TNFAIP3的抗体
15概述 产品名称 抗TNFAIP3的抗体 描述 兔单克隆抗体 to TNFAIP3 宿主 Rabbit 经测试应用 适用于: ICC/IF, WB, IHC-P, Flow Cyt 种属反应性 与反应: Mouse, Human 免疫原 Synthetic peptide with...
查看全文品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
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HAOKEBIO | HK210254M | NRF2兔多克隆抗体 | 100ul | 支 | 1960 |
human ovary tumor tissue, human breast cancer tissue, human colon cancer tissue, human kidney tissue, human liver cancer tissue, human renal cell carcinoma tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
NRF2, also named as NFE2L2, belongs to the bZIP family and CNC subfamily. It is a transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. NRF2 is important for the coordinated up-regulation of genes in response to oxidative stress. It may be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.Nrf2 is a key player in the regulation of genes encoding for many antioxidative response enzymes.The expression of NRF2 may be induced under oxidative stress (PMID:14567983).In lung cancer, Nrf2 activation in malignant cells has been associated with tumor progression and chemotherapy resistance(PMID:20534738). Identifying patients with abnormal NRF2 expression may be important for selection for chemotherapy in NSCLC. As new investigators break into the emerging field of Nrf2 research, confusion regarding the correct migratory pattern of Nrf2 is causing doubts about the accuracy and reproducibility of published results. This letter provides solid evidence that the biologically relevant molecular weight of Nrf2 is ~95-110 kDa and not the predicted ~55-65 kDa based on its 2-kilobase open reading frame. The data discussed and presented here will hopefully lead to a uniform acceptance that future experiments and publications should be designed around detecting Nrf2 at the correct molecular weight of ~95-120 kDa (PMID: 22703241).
概述 产品名称 抗TNFAIP3的抗体 描述 兔单克隆抗体 to TNFAIP3 宿主 Rabbit 经测试应用 适用于: ICC/IF, WB, IHC-P, Flow Cyt 种属反应性 与反应: Mouse, Human 免疫原 Synthetic peptide with...
查看全文品牌 商品编码 商品名称 规格 单位 单价 HAOKEBIO HKI0671A PD-1兔单克隆抗体 100ul 支 1500 Applications Tested Applications: FC, IF, IHC, WB,ELISA Cited Applicati...
查看全文品牌 商品编码 商品名称 规格 单位 单价 KAOKEBIO HK210094M CDK6兔多克隆抗体 100ul 支 1960 Applications Tested Applications: FC, IF, IHC, IP, WB,ELISA Cited ...
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