CDK3兔多克隆抗体
159Applications Product Information Immunogen Information Background
查看全文品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
---|---|---|---|---|---|
KAOKEBIO | HK210032L | BAX兔多克隆抗体 | 200ul | 支 | 2800 |
KAOKEBIO | HK210032M | BAX兔多克隆抗体 | 100ul | 支 | 1960 |
BAX, also named as BCL2L4, is a pro-apoptotic member of the Bcl-2 protein family, which plays a pivotal role in controlling cell life and death. Bax largely localizes to the cytoplasm of healthy cells, but accumulates on the outer mitochondrial membrane upon apoptosis induction (PMID: 9108035). BAX can commit a cell to apoptosis by translocation from the cytosol to the mitochondria and permeabilization of the outer mitochondrial membrane, which leads to the release of cytochrome c from mitochondria (PMID: 21763611). The expression of BAX is upregulated by the tumor suppressor protein p53, and BAX has been shown to be involved in p53-mediated apoptosis (PMID: 8183579).
Tested Applications: IF, IHC, WB,ELISA Species Specificity: human, mouse Cited Species: human Positive...
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