杭州浩克生物
XBP1兔多克隆抗体
152Applications Product Information Immunogen Information Background
查看全文BCL2L1兔多克隆抗体
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| KAOKEBIO | HK210038M | BCL2L1兔多克隆抗体 | 100ul | 支 | 1960 |
Applications
Tested Applications:
FC, IF, IHC, IP, WB,ELISA
Cited Applications:
ChIP, IHC, WB
Species Specificity:
human, mouse, rat
Cited Species:
goat, human, mouse, rat, sheep, zebrafish
Positive WB detected in:
A549 cells, Raji cells, mouse placenta tissue, HepG2 cells, C6 cells, Jurkat cells, K-562 cells, human placenta tissue, NIH/3T3 cells, RAW264.7, HeLa cells, rat brain tissue
Positive IP detected in:
K-562 cells
Positive IHC detected in:
human lung cancer tissue, human colon tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected in:
NIH/3T3 cells
Positive FC detected in:
Jurkat cells
Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500
IF : 1:10-1:100
Product Information
Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information
Full name:
BCL2-like 1
Calculated molecular weight:
26 kDa
Observed molecular weight:
30 kDa
Gene symbol
BCL2L1
Synonyms
Apoptosis regulator Bcl X, BCL2L1, Bcl-XL
Background
BCL2L1 is a member of the BCL-2 protein family. BCL2L1 is expressed as three isoforms, Bcl-X(L),Bcl-X(s) and Bcl-X(beta) , and is located at the outer mitochondrial membrane. The Bcl-X(L) isoform is a 233 amino acid protein, acting as an apoptotic inhibitor. Bcl-XL can forms heterodimers with BAX, BAK or BCL2, and the heterodimerization with BAX does not seem to be required for anti-apoptotic activity. The Bcl-X(s) isoform is a shorter variant that is 178 amino acids in length and lacks a 63 amino acid region (amino acids 126-188), acting as an apoptotic activator. Bcl-X(beta) is a 227 amino acid protein. This antibody can recognize Bcl-XL, Bcl-X(s) and Bcl-X(Beta).
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