杭州浩克生物
BST2兔多克隆抗体
124Applications Product Information Immunogen Information Background
查看全文ARL13B兔多克隆抗体
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| KAOKEBIO | HK210015L | ARL13B兔多克隆抗体 | 200ul | 支 | 2800 |
Applications
Tested Applications:
IF, IHC, IP, WB,ELISA
Cited Applications:
IF, IHC, IP, WB
Species Specificity:
human, mouse, rat, Canine
Cited Species:
canine, chicken, human, mouse, pig, rat, sheep, Xenopus, zebrafish
Positive WB detected in:
mouse liver tissue, NIH/3T3 cells, L02 cells, mouse kidney tissue, rat liver tissue, mouse brain tissue
Positive IP detected in:
L02 cells
Positive IHC detected in:
mouse brain tissue, human testis tissue, human liver tissue, human kidney tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected in:
MDCK cells, hTERT-RPE1, mouse embryonic fibroblasts, NIH3T3 cells
Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:500
IF : 1:50-1:500
Product Information
Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information
Full name:
ADP-ribosylation factor-like 13B
Calculated molecular weight:
48 kDa
Observed molecular weight:
40-48 kDa, 66 kDa
Gene symbol
ARL13B
Synonyms
ARL13B, ARL2 like protein 1, ARL2L1, JBTS8
Background
ARL13B, also named as ARL2L1, is a small ciliary G protein of the Ras superfamily. Localized in the cilia, it is required for cilium biogenesis and sonic hedgehog signaling. Defects in ARL13B are the cause of Joubert syndrome (JS) which is an autosomal recessive disorder characterized by a distinctive cerebellar malformation (PMID: 19906870).This antibody detects two specific bands at 60 kDa and 48 kDa. Arl13b is predicted to be a 48 kDa protein, and the 60 kDa band is likely to represent a modified form of Arl13b. ARL13B can be used to mark the cilia (PMID:22072986).
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